Khadem, Monireh
Assistant Professor, Department of Occupational Health Engineering, Faculty of Public Health, Tehran University of Medical Sciences, Tehran, Iran
[ 1 ] - Fabrication and Optimization of Molecularly Imprinted Nanofibers in Assessment of Occupational Exposure to 5-fluorouracil
Background and purpose: Cytotoxic drugs are a group of chemicals that raise concerns over the health of healthcare professionals. Therefore, accurate methods are needed to investigate the traces of these drugs. This study was done to fabricate and optimize molecularly imprinted membrane as a specific absorbent in assessment of occupational exposure to 5-fluorouracil. Materials and methods: 5-F...
[ 2 ] - Protective Effect of Salvia officinalis Extract on Deltamethrin-induced Hepatotoxicity in Rats
Background and purpose: Deltamethrin is one of the major pesticides used in agriculture to control pests. Oxidative stress is one of the deltamethrin toxicity mechanisms. Different antioxidants have been investigated to deal with the oxidative damage of toxic substances. The purpose of this study was to evaluate the protective effect of Salvia officinalis extract against deltamethrin-induced he...
[ 3 ] - Antioxidant and Protective Effects of Plant Extract against Deltamethrin-induced Oxidative Stress in Liver and Kidney – A Review
Deltamethrin is one of the most commonly used Pyrethroid around the world. Oxidative stress is one of the most deltamethrin toxicity mechanisms. According to many studies, it has been shown that the liver, due to its role, is the main source of accumulation of high concentrations of deltamethrin metabolites. Also the kidney plays a very important role in regulating homeostasis of the body and r...
[ 4 ] - DEVELOPMENT OF A PHYSIOLOGICALLY BASED TOXICOKINETIC MODEL FOR HUMAN EXPOSURE RISK ASSESSMENT OF METHYLENE DIPHENYL DIISOCYANATE(MDI)
Introduction: Given the lack of a developed physiologically based toxicokinetic (PBTK) model for human systemic exposure assessment of methylene diisocyanate (MDI) and prediction of its urinary metabolites, this study aims to develop a PBTK model for exposure risk assessment of MDI. Methods and Materials: In this study, to assess the potential exposure to the MDI, a PBTK model was constructed ...