NAILA ABRAR

HITEC Institute of Medical Sciences, National University of Medical Sciences, Rawalpindi, Pakistan

[ 1 ] - Comparative study of protective effect of silymarin and n-acetyl cysteine on isoniazid induced hepatotoxicity in mice

Drug induced liver injury (DILI) leads to acute hepatitis in 10%, liver failure, and death in 30%. One of the major drugs causing DILI is Anti-tuberculous drugs and since tuberculosis is affecting 1/3rd of the total world population, their use is quite common. Use of Isoniazid (INH) is limited owing to hepatotoxicity following the stress produced by oxidative species. Silymarin has hepatoprotec...

Co-Authors

ABID HUSSAIN 1  

LUBNA DANISH 1  

MANZOOR KHAN 1  

MARVA SANDHU 1  

RIFFAT SIDDIQ 1  

SARWAT JAHAN 1