Farinaz Saremnejad

[ 1 ] - Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug

Objective(s): 4-aminosalicylic acid (4-ASA) is an isomer of mesalazine that has recently been shown to be effective against inflammatory bowel disease (IBD), and more specifically, ulcerative colitis. However, the majority of orally administered 4-ASA is readily and extensively absorbed from the stomach and small intestine, so only a small amount is transported to the ...