Ehsan Saboory
Zanjan Metabolic Diseases Research Center, Zanjan University of Medical Sciences, Zanjan, Iran
[ 1 ] - Prenatal stress increased γ2 GABAA receptor subunit gene expression in hippocampus and potentiated pentylenetetrazol-induced seizure in rats
Objective(s): Stress during pregnancy is able to bring extensive effects on neurobehavioral development in offspring. The GABAergic system plays a pivotal role in neuronal excitability, which can be affected by prenatal stress (PS). This study aimed to evaluate impact of the PS on γ2 subunit of gamma-aminobutyric acid A (GABAA) receptor gene expression in the hippocamp...
[ 2 ] - Effect of Predatory Stress Before Fertilization on Body Weight and Pentylenetetrazole-Induced Seizure in Rat Offspring
Background and Objective: Spermatogenesis and oogenesis stress is a primary epigenetic element that can cause lifelong modifications in neural system functions. This study was designed to elucidate whether preconceptional stress during spermatogenesis and oogenesis affects the seizure behaviors and body weight of the offspring later in life. Materials and Methods: In this experimental study, 1...
[ 3 ] - S-Allyl Cysteine Mitigates Kidney Dysfunctions in the Rat Models of Preeclampsia and Eclampsia: The Possible Role of TNF-α and IL1-β
Background and Objective: Preeclampsia (PE) is a pregnancy complication with the signs of kidney damage. The effect of S-Allyl-cysteine (SAC) on inflammatory cytokines was evaluated to prevent PE-induced renal complications. Materials and Methods: Wistar rats were divided into seven groups: 1) control, 2) PE, 3) EC, 4) PE+SAC50, 5) PE+SAC200, 6) EC+SAC50, and 7) EC+SAC200. In Groups 1-3, the r...