Maleknia , Shayan
Biopharmaceutical Research Center, AryoGen Pharmed Inc., Alborz university of Medical Sciences, Karaj, Iran
[ 1 ] - Optimization of HER2-based and cell-based ELISA for detection of trastuzumab biosimilar
Introduction: ELISA is a sensitive, specific, reproducible and fast method to quantify the biological activity of antibodies. Trastuzumab is a humanized monoclonal antibody against HER2 receptors which prevents the initiation of downstream signaling pathway. Trastuzumab can be used as a positive control in the ELISA experiments for anti-HER2 antibodies. Additionaly, insufficient washing and blo...
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