Marjan Saeedi

[ 1 ] - A comparative study of estrogen receptor beta expression in melanoma and benign melanocytic lesions

Background: Malignant melanoma is the most aggressive form of skin cancer. In contrast to other tumors, the role of estrogen in the initiation and progression of melanoma remains unclear. The aim of this study was to evaluate estrogen receptor beta protein expression in human melanoma tissues and in the benign melanocytic lesions. Method: Twenty-one patients, 11 with cutaneous melanoma and 10 w...

[ 2 ] - Palpable Purpura: An Uncommon Side Effect of Alexandrite Laser Hair Removal

A 40-year old woman was visited at our clinic with a history of palpable purpura appearing after alexandrite laser (Apogee 5500 Alex, 15mm spot shot, 755 nm wave length, 18 j/cm2 fluence) hair removal. The skin lesions were located bilaterally on the lower extremity (Figure1). Other physical examinations were unremarkable. The patient had no history of taking medications, underlying systemic di...

[ 3 ] - A Case of Lipomembranous Panniculitis Associated with Rheumatoid Arthritis

Lipomembranous panniculitis is a special type of fat necrosis which has been associated with several clinical conditions, mainly chronic venous insufficiency and connective tissue disorders such as lupus profundus, morphea, systemic sclerosis, and dermatomyositis .We report a 50 yearold woman with known rheumatoid arthritis who presented with a painful indurated erythematous plaque on her right...

[ 4 ] - Interplay among Antioxidants and Oxidants in Psoriasis

Background: The etiology of psoriasis, a chronic inflammatory skin disease, has not been elucidated. However, Oxidant / antioxidant imbalance is suspected.The aim of this study was to evaluate oxidant / antioxidant status in psoriatic patients.Method: forty two psoriatic patients and 42 age and sex matched controls were recruited for this study. Serum total antioxidant ...

[ 5 ] - An Adult Case of Hydroa Vacciniforme

Hydroa vacciniforme (HV) is a rare acquired photodermatosis, usually with onset in childhood and characterized by vesicles, crust and scar formation that follow exposure to sunlight.Vacciniform scars of face and dorsa of the hands are common features but oral ulcer and eye signs also rarely occur. It usually resolves before adult age. A rare manifestation of the disease would be persisten...

[ 6 ] - CASE: Erosive Nodule on the Vulval Skin

A 64-year-old Iranian woman presented with a genital erosive skin lesion that she had noticed from two years ago. On physical examination, a 20 to 25 millimeter purplish lesion was observed on the vulval skin (Figure 1). The indurated lesion showed a small central erosion measuring 3 to 5 mm. Inguinal lymph nodules were not palpable. A skin biopsy specimen was obtained from the eroded les...

[ 7 ] - Staphylococcus Aureus Carriage in Patients with Psoriasis

Background: The aggravating role of Staphylococcus aureus is well known in atopic dermatitis but has not yet been proven in psoriasis. The role of Staphylococcus aureus superantigens is emphasized in the initiation, maintenance and complications of psoriasis. We investigated the frequency of nasal, axillary, and perineal carriage of Staphylococcus aureus (SA) in patients with psoriasis and its ...

[ 8 ] - CASE: Multiple painful nodules on the back

A 43-year-old middle-eastern woman was visited with a 15-year history of multiple painful cutaneous nodules on her back. The first lesion appeared on her back when she was 28 years old. As she aged, the lesions became larger, more numerous, and more painful with cold or physical contact. Her medical history was not significant. The patient’s medications included naproxen, calcium-D, and vitamin...