Tavasoli, Alireza

[ 1 ] - The protective effects of vitamin E and C against oxidative stress induced by sulfasalazine in the testis of male adult rats

Background & Objective: Sulfasalazine (SASP) is a drug used for the treatment of inflammatory bowel diseases. SASP causes testicular damage. The aim of this study was to verify whether or not an additional supply of vitamin E or C or together prevent the toxic effect of SASP on the rat spermatogenesis. Materials & methods: Adult male wistar rats (150-200 gr) were divided into five groups (n=8)...

[ 2 ] - The Evaluation of Melatonin Effect Against The Early Effect of Ionizing Radiation Induced Lung Injury

Background & Objective: Lung is a radiosensitive organ. Patients who are undergoing radiation therapy in their chest are subjected to radiation pneumonitis in the early phase and pulmonary fibrosis in the late one. Melatonin scavenges free radicals directly and acts as an indirect antioxidant through the activation of major antioxidant enzymes as well. The aim of the study thus is to investiga...