Mahnaz Qomi

Active Pharmaceutical Ingredients Research Center, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran (APIRC)

[ 1 ] - N-octyl-modified magnetite NPs for optimization of solid phase extraction for trace analysis of phenytoin in real samples

objective: Phenytoin is an anti-seizure medication used to treat epilepsy, as well as to control arrhythmias (irregular heartbeat) and to treat migraine headaches and nerve pain. It is recommended to determine the amount of this drug in the blood to control the seizure and prevent its toxicity. In the present study, a sensitive and simple procedure based on the dispersive solid phase extraction...

[ 2 ] - Optimized preconcentration of Imatinib using dispersive liquid-liquid microextraction coupled with HPLC-UV

Background: Imatinib is an antineoplastic agent acting as a tyrosine kinase inhibitor to treat cancer such as lymphoblastic leukemia. The dosage of the anticancer drugs plays a critical role in the survival of the patients. For this reason, the patient's plasma and urine samples should be monitored to obtain the necessary information regarding the toxicity of the drug. In this study, the applic...