Masomeh Hoseini Rad

Department of Chemistry, Qom Branch, Islamic Azad University, Qom, I. R. Iran

[ 1 ] - Multi-component synthesis of spiro[indoline-3,4'-pyrrolo[3,4-c]pyrazoles] using Zn(BDC) metal-organic frameworks as a green and efficient catalyst

In this research, a series of spiro compounds was efficiently synthesized via one-pot multi component reactions of isatins, aryl amines, dimethyl acetylenedicarboxylate and hydrazine in the presence of Zn(BDC) MOF as catalyst. The key superiority of this process is high yields, easy work-up, short reaction times, and purification of the products by the non-chromatographic system. The study of t...