Rana Rafiei

Skin Research Center, Dermatology Department, Guilan University of Medical Sciences, Razi Hospital,

[ 1 ] - Unilateral eyelid edema and mucosal involvement as the first presentations of Wegener granulomatosis

Background: Wegener granulomatosis or granulomatosis with polyangiitis is a pauci-immune small vessel vasculitis which is usually associated with anti-neutrophil cytoplasmic antibodies (ANCA) mainly in old men. This small vessel vasculitis is usually characterized by necrotizing granulomatous inflammation with multiorgan involvement. Kidneys could be involved as the main and life-threatening co...

[ 2 ] - Cutaneous amyloidosis as the first presentation of Waldenstrom macroglobulinemia

Background: Waldenstrom macroglobulinemia is a lymphoplasmacytic lymphoma with elevated serum immunoglobulin M and multi-organ involvement. Primary systemic amyloidosis usually develops due to immunoglobulin light chains depositions in different organs due to an underlying gammopathy. Case presentation: Our patient was an 86-year-old man with macroglossia, ecchymotic patches and bullous lesion...