Mohammadi-Farani, Ahmad

Kermanshah University of Medical Sciences

[ 1 ] - Cytotoxicity evaluation of a new series of naphthalimide derivatives against human cancer cell lines

Introduction: Cancer has been known as one the main causes of the death in the world. In recent researches, discovery of effective, selective and safe medications is a priority and emergency. In recent reports, the role of lipoxygenases (LOX) has been confirmed in neoplastic diseases. Some isoenzymes such as 5, 12 and 15 have more importance in the neoplasia. According to the efficacy of naphth...

[ 2 ] - Investigation of the plasma levels of CCL-17 and CCL-25 and their receptor gene expression in rheumatoid arthritis patients

Background and Aim: Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of unknown etiology.  The chemokines and their related receptors have a pivotal role in migration and homing of leukocyte involved in the pathogenesis of RA. The goal of this study was to measure the plasma levels of CCL-17 and CCL-25 and their receptors gene (CCR4 and CCR9) expression in rheumatoid arthritis pa...