Samane Jahanabadi
Department of Pharmacy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
[ 1 ] - Vitamin D suppresses cellular pathways of diabetes complication in liver
Objective(s): The aim of this study was to investigate the effect of vitamin D on glucose metabolism, as well as the expression of five key genes involved in the development of diabetes complications in liver tissue of diabetic rats. Materials and Methods: Twenty-four male Sprague–Dawley rats were randomly divided into three groups (8 ra...
[ 2 ] - Evaluation of the antidepressant effects of pioglitazone in ovariectomized mice through nitric oxide pathway
Background: Pioglitazone is the selective PPAR-γ receptor agonist, which is prescribed for the treatment of type 2 diabetes and may also have antidepressant effects. Nitric oxide (NO) has been involved in some crucial roles, including learning, cognition and neurogenesis as well as some neurodegenerative diseases, including Parkinson, Alzheimer's disease (AD) and depression. Reduced estrogen le...