Jhon Camacho-Cruz
MD Pediatrician, Associate Instructor Department of Pediatrics, Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá, D.C. Colombia. Grupo de Investigación Materno – Infantil. Línea Pediatría.
[ 1 ] - Hutchinson-Gilford Progeria Syndrome
The Hutchinson-Gilford syndrome or progeria is a laminopathy generated by mutations that affect LMNA gene. This produces an abnormal protein named progerine which alters the formation of the cellular membrane inducing premature aging of all cells. In the present review aspects related to the pathophysiology and clinical characteristics of this syndrome are shown.