Norouzi, Akram
MSc in Clinical Biochemistry, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
[ 1 ] - Effect of Trehalose on the Expression of Heat Shock Protein 70 Gene in PC12 Cells Treated with Hydrogen Peroxide
Background and purpose: Oxidative stress is implicated in the pathogenesis of various diseases, including neurological disorders. In such stressful conditions, heat shock protein 70 (HSP70) protects cells, thus its pharmacological induction can be protective. The disaccharide trehalose exhibits various beneficial effects, including antioxidative effect. However, its impact on HSP70 is not obvio...
[ 2 ] - Protective Effect of Trehalose Against H2O2-induced Cytotoxicity and Oxidative Stress in PC-12 Cell Line and the Role of Heat Shock Protein-27
Background: Oxidative stress has been shown to be an important factor, which plays a significant role in the pathogenesis of neurodegenerative disorders. Heat Shock Protein-27 (HSP-27) has been implicated in antioxidant responses against oxidative stress. Trehalose is a natural disaccharide widely used in a variety of food products with demonstrated protective effects against several neurodegen...
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