Ashraf Mohamadkhani
Digestive Disease Research Centre, Shariati Hospital, Tehran University of Medical Science, Tehran, Iran
[ 1 ] - The Increased Level of Serum p53 in Hepatitis B-Associated Liver Cirrhosis
Background: The ability of tumour suppressor protein p53 (P53) to regulate cell cycle processes can be modulated by hepatitis B virus (HBV). While preliminary evidences indicates the involvement of protein-x of HBV (HBx) in altering p53 DNA binding, no further data have been accumulated for the significance of serum p53 in chronic hepatitis B virus infected patients. Methods: 72 non-cirrhotic a...
[ 2 ] - Inflammatory Cytokines and type 2 diabetes
Inflammatory cytokines increase in patients with type 2 diabetes (T2D) and metabolic syndrome. This review focuses on inflammatory cytokines such as C-reactive protein (CRP), tumor necrosis factor (TNF-α), and adiponectin, a cytokine produced by adipose tissue and associated with insulin sensitivity. Despite the major role of cytokines in the development of T2D, in the case of adiponectin still...
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