Jamshidi, Hamid Reza
[ 1 ] - Effects of Parathion Toxin on Glutamate Dehydrogenase Enzyme Activity and Diabetes Induction
Introduction: The main propose of this study was to determine the effect of parathion on activity of glutamate dehydrogenase (GDH) as a key enzyme in second phase secretion of insulin and to determine serum glucose levels in rats. Methods: To conduct the study, 35 rats were randomly divided into five groups (n=7). The serum glucose level of each group was measured and the total average was ca...
[ 2 ] - Evaluation of Glutamate Dehydrogenase Activity and Insulin Secretion in Mice Exposed to Dexamethasone
Background and Aims: Diabetes is one of the most important endocrine disrupters and is associated with various hormones, including those that can lead to diabetes. Glucocorticoid use may lead to insulin resistance. Dexamethasone is one of these glucocorticoid compounds. Glutamate dehydrogenase plays a key role in the production of glutamate in the secretion of insulin. Based on these hormonal i...
[ 3 ] - Effect of Sodium Selenide on Renal Toxicity Induced By Mercuric Chloride in Rat
Background and Aims: Mercury, with its oxidative activity, causes damage to the antioxidant enzymes thus resulting in physiological disorders. Sodium selenide is an antioxidant that protects antioxidant enzymes. The aim of this study was to investigate the protective effect of sodium selenide on renal toxicity induced by mercuric chloride in rats. Materials and Methods: Animals were divided in...
[ 4 ] - Effects of Thymol on Co-amoxiclav-Induced Hepatotoxicity in Rats
Background and Aims: Hepatotoxicity induced by Co-amoxiclav has been indicated in multiple studies. Thymol is the main constituent of the Thymus vulgaris essential oil that has antioxidant properties. Even though thymol can exhibit antioxidant activity in vivo models, there is a lack of evidence about the thymol’s effectiveness in drug-induced liver injury. Thus, the present study was conducted...
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