Gholamreza Asadikaram

Professor, Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Sciences AND Department of Biochemistry, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran

[ 1 ] - Effects of Opium Addiction and Cigarette Smoking on Hematological Parameters

Background: The aim of the present study was to investigate the effects of opium addiction and cigarette smoking on the complete blood count (CBC).Methods: Eighty-six male subjects, including 31 opium-addicted cigarette smokers (OACS), 19 opium-addicted non-cigarette smokers (OANCS), 17 non-opium-addicted cigarette smokers (NOACS), and 19 non-opium-addicted non-cigarette smokers (NOANCS) parti...

[ 2 ] - The Effect of Acute and Chronic Morphine on Some Blood Biochemical ‎Parameters in an Inflammatory Condition in Gonadectomized Male Rats

Background: Opiates affect blood factors as well as pain and inflammation in a gender-dependent manner. The aim of the present study was to evaluate the effects of morphine on serum glucose, cholesterol, triglycerides, and urea in gonadectomized and inflammation conditions. Methods: Animals were divided as follows: control group, carrageenan and chronic morphine recipients, acute morphine recip...

[ 3 ] - Effects of Different Concentrations of Opium on the Secretion of ‎Interleukin-6, Interferon-γ and Transforming Growth Factor Beta Cytokines ‎from Jurkat Cells

Background: The risk of infectious, autoimmune and immunodeficiency diseases and cancers rise in opioid addicts due to changes in innate and acquired immune responses. Three types of opioid receptors (К،δ،μ) are expressed on the surface of lymphocytes and mononuclear phagocytes. The present study was designed to examine the effects of different concentrations of opium on the secretion of some c...