براتی, مهدی

. دکترای ایمونولوژی، گروه ایمنی شناسی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، مشهد، ایران 4. کمیته تحقیقات دانشجویی، دانشگاه علوم پزشکی مشهد، مشهد، ایران

[ 1 ] - اثر بربرین بر بیان ژن Bcl-2 در بیماران لوسمی لنفوسیتی مزمن در مقایسه با گروه کنترل

Background and purpose: Anti-apoptotic protein Bcl-2 prevents apoptosis through the mitochondrial pathway and high-level expression of Bcl-2 is required for survival of chronic lymphocytic leukemia (CLL). Berberine (BBR) is an alkaloid that induces apoptosis of cancer cells via mitochondrial pathways. The aim of this study was to investigate the effect of Berberine on Bcl-2 gene expression in p...

[ 2 ] - The State of Peripheral Blood Natural Killer Cells and Cytotoxicity in Women with Recurrent Pregnancy Loss and Unexplained Infertility

Objective : The prognostic value of peripheral natural killer (pNK) cells, as a screening test in women with recurrent pregnancy loss (RPL) and unexplained infertility is still a matter for discussion. The aim of this study was to compare the percentage of circulating CD56+NK cells, CD69 and perforin markers between women with unexplained infertility and RPL with healthy control group. Material...