MAHDI SADEGHI
Medical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
[ 1 ] - Production, quality control, and biodistribution studies of 141Ce-EDTMP as a potential bone pain palliation agent
The purpose of the present work was to introduce 141Ce-EDTMP as a novel potential future pain palliative agent to patients suffering from disseminated skeletal metastases and diagnostic imaging radioisotope as well. Cerium-141 [T1/2 = 32.501 days, Eβ (max) = 0.580 (29.8%) and 0.435(70.2%) MeV, Eγ = 145.44 (48.2%) keV] possesses radionuclidic properties suitable for use in palliative therapy of ...
[ 2 ] - Toxicity of nano and bulk forms of cerium oxide in different cell lines
In recent years, nanotechnology has gained serious attention for diagnosis, prevention and treatment roles. In this study we synthesized nanoceria or CeO2NPs (cerium oxide nanoparticles) and compared toxicity of cerium oxide powder in nano and bulk forms in two cancerous and one normal cell lines. The cell lines were cultured in a standard humidified incubator, at 37 °C in a 5% CO2 atmosphere, ...
[ 3 ] - Proof of Symmetric Dose Distribution in Mammosite Applicator in Breast Brachytherapy with MCNP Simulation
Introduction: In brachytherapy treatments, high-dose sources are used in interstitial placement. In this paper, the modeling of a common breast cancer treatment applicator called MammoSite is done by the Monte Carlo simulation code. Then, to study and calculate the amount of doses in the breast and the dose rate of the organs at risk of radiation, including: lungs, ribs and ski...
[ 4 ] - Calculation of absorbed dose rate in the lungs, ribs and skin by the mammosite applicator in breast cancer brachytherapy with MCNP
Introduction: Breast cancer is the most common cancer among women. Brachytherapy is one of the ways to treat breast cancer. In brachytherapy treatments, high-dose sources are used in interstitial placement. Here, Iridium-192 is used. This source emits gamma rays with energies ranging from 136 kV to 1060 kV electron volts. The activity of the used spring is 10 Ci. The simulated ...
[ 5 ] - Calculation of Neutron Dose Ratio of Heart, Lung and Liver due to breast cancer Proton Therapy using MCNPX code
Introduction: The proton beam produced in particle accelerators has an appropriate therapeutic potential. In this research, proton therapy of breast cancer is simulated using the MCNPX code in a MIRD phantom, also the contribution of scattered neutron dose during the proton therapy were calculated for the Heart, Lung and Liver. Materials and Methods: For si...
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