باقری, ابوذر
استادیار، گروه بیوشیمی بالینی، بیوفیزیک و ژنتیک، مرکز تحقیقات بیولوژی مولکولی و سلولی، دانشگاه علوم پزشکی مازندران، ساری، ایران
[ 1 ] - مروری بر اثرات سیلیبینین بر روی بیان miRNA های مختلف در سرطان
MicroRNAs (miRNAs) are small non-coding RNAs that regulate the expression of about 60% of human genomes. Silibinin or mixture of silybin A and B is a flavonolignans that constitute 70-80% Silymarin which is considered to be its main effective ingredient. Silibinin revealed antioxidant and anti-inflammatory effects by scavenging free radicals, improving antioxidant enzymatic activities, and supp...
[ 2 ] - Genetic Counseling for Families with Sporadic Intellectual Disability in North of Iran: A Retrospective Study
Background Intellectual Disability (ID) is a heterogeneous disorder, in which at least 600 genes participate. The present study aimed to identify the effect of genetic counseling and consanguinity marriage in Iranian families with sporadic mental disability. Materials and Methods: In th...
[ 3 ] - Doxorubicin and Doxorubicin-loaded Nanoliposome Triggers Hepatocyte Cells Senescence through Accumulation of Inflammatory Factors and Activation of P53
Background and purpose: Induction of cellular senescence is indicative of new strategy to prevent abnormal proliferation of cancer cells. Doxorubicin (DOX) is gaining attention for its neoplasia suppressive and inhibitory properties, but its clinical utility is limited due to irreversible effects on non-target cells/tissues. In this way, nanoliposomal structures were developed in drug delivery ...
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