جلیلی, ارسلان

دانشگاه ازاد اسلامی واحد تهران شرق

[ 1 ] - بررسی بیان ژن های IL4، TNFα، TGFβ و IFNγ در تائید پلاریزاسیون ماکروفاژهای M1 و M2 حاصل از کشت مونوسیت های انسانی

background: Classical macrophages (M1) and alternative macrophages (M2) are responsible for various functions in order to maintain homeostasis. BCG vaccine and hydatid cyst fluid can be examples of stimulants which can cause M1and M2 macrophage polarization. Evaluating the expression of markers such as IFNγ and TNFα for M1 phenotype and TGFβ and IL4 for M2 phenotype is one of the confirmatory w...

[ 2 ] - Signaling pathways involved in chronic myeloid leukemia pathogenesis: the importance of targeting Musashi2-Numb signaling to eradicate leukemia stem cells

Objective(s): Chronic myeloid leukemia (CML) is a myeloid clonal proliferation disease defining by the presence of the Philadelphia chromosome that shows the movement of BCR-ABL1. In this study, the critical role of the Musashi2-Numb axis in determining cell fate and relationship of the axis to important signaling pathways such as Hedgehog and Notch that are essential ...