Vahid Khakizadeh

[ 1 ] - Four-component Cascade Reaction was Programmed and Catalyzed by B(OH)3.H2O as an Efficient and Green Catalytic System

An aqueous solution of boric acid, as an efficient and green catalytic system, was efficiently utilized four-component cascade reaction of aryl aldehydes, dimedone, β-ketoesters and ammonium acetate to give hexahydroquinolines. By the reaction of boric acid with water, H+ was generated and efficiently catalyzed the reaction under mild and green condition. Also, optimization of the reaction cond...