Zahra Abdollahi

Department of Medicinal Chemistry, Faculty of pharmacy and Pharmaceutical sciences research center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

[ 1 ] - Cholinesterase Inhibition Activity and Docking Simulation Study of Coumarin Mannich Base Derivatives

Inhibition of acetylcholinesterase and butyrylcholinesterase (AChE and BuChE) as two major forms of cholinesterases (ChEs) is considered as the common approach for the treatment of Alzheimer's disease (AD). The present study was done to explore the anticholinesterase inhibition property of coumarin Mannich base derivatives. A series of cumarin Manich bases were synthesized (4a-h) through one-po...