Ali Kiani

Department of medical Chemistry, school of pharmacy, International campus, Tehran University of Medical Science (IC-TUMS),Tehran, Iran.

[ 1 ] - Cholinesterase Inhibition Activity and Docking Simulation Study of Coumarin Mannich Base Derivatives

Inhibition of acetylcholinesterase and butyrylcholinesterase (AChE and BuChE) as two major forms of cholinesterases (ChEs) is considered as the common approach for the treatment of Alzheimer's disease (AD). The present study was done to explore the anticholinesterase inhibition property of coumarin Mannich base derivatives. A series of cumarin Manich bases were synthesized (4a-h) through one-po...