Shyam Gurram

Department of Microbiology, Kakatiya University, Warangal 506009, AP, India

[ 1 ] - Biotransformation of Albendazole by Cunninghamella blakesleeana:Influence of Incubation Time, Media, Vitamins and Solvents

The present investigation was aimed at studying the effect of incubation period, media, vitamins and solvents on biotransformation of albendazole by Cunninghamella blakesleeana. The transformation was evaluated and identified by high performance liquid chromatography (HPLC) and the structures of the transformed products were assigned by liquid chromatography-tandem mass spectrometry (LC/MS/MS) ...

[ 2 ] - Oxidation of Meloxicam by Streptomyces griseus

The aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. Among the actinomycetes screened, Streptomyces griseus NCIM 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in S. griseus NCIM 2623...

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