Farinaz Behfarjam

Department of Biology, Faculty of Science, University of Kurdistan, Sanandaj, Iran

[ 1 ] - Association of Two Polymorphic Codons in P53 and ABCC1 Promoter with Prostate Cancer

Background: In prostate cancer, mutated p53 alleles typically contain missense single-base substitution in codon 72 that resides within exons 5-8. Stable p53 proteins in tumor cell nuclei have been associated with malignancy. A role of p53 is the regulation of drug transporters like ABCC1 (MRP1) by an effect on promoter region. Objectives: The objective of this study was to identify association...