Yongmin Yan

301 xuefu road, zhenjiang, jiangsu

[ 1 ] - Expression of Recombinant Phosphodiesterase 3A and 3B Using Baculovirus Expression System

Background: Phosphodiesterase 3A (PDE3A) and phosphodiesterase 3B (PDE3B) play a critical role in the regulation of intracellular level of adenosine 3´,5´-cyclic monophosphate (cyclic AMP, cAMP) and guanosine 3´,5´-cyclic monophosphate (cyclic GMP, cGMP). Subsequently PDE3 inhibitors have shown to relax vascular and inhibit platelet aggregation in cardiovascular disease. Objectives: In th...

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