Pouria Jarsiah

Department of Toxicology and Pharmacology, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

[ 1 ] - Hepatotoxicity and ALT/AST Enzymes Activities Change in Therapeutic and Toxic Doses Consumption of Acetaminophen in Rats

Acetaminophen (APAP) poisoning is the most common drug intoxication, which often leads to acute liver failure (ALF). In this study, the effects of different doses of APAP on aminotransferases (AST and ALT) and liver pathological lesions were assessed in young rats. 32 male albino Wistar rats were randomly selected and divided into eight groups. In case groups, three groups after one hour, and 3...