Samira Sadeghi
Genetics Division, Biology Department, Faculty of Sciences, University of Isfahan, Isfahan, Iran
[ 1 ] - Optimization of Real Time PCR for Precise Measurement of HER2 Overexpression in Breast Cancer Specimens
Background: Breast cancer is one of the most prevalent malignancies among women in various countries. HER2 overexpression, which is due to different reasons, occurs in 20-30% of breast cancers. HER2 gene encodes an 185kDa transmembrane glycoprotein with 1255 amino acids. This active product triggers downstream intracellular signaling pathways inducing cell proliferation and cell survival. These...
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