Ramin Saravani
Cellular and Molecular Research Center, Zahedan University of Medical Sciences, Zahedan, Iran - Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
[ 1 ] - Common Variations in Perilipin rs1052700 and FTO rs3751812 Genes, Central Obesity, and Risk Type-2 Diabetes
Background: Perilipins are proteins at the external level of the lipid glob in adipocytes steroid-generating cells and play a central role in lipid storage and breakdown. FTO gene is associated with Type-2 diabetes (T2D) and increased fat mass. Association of Perilipin and FTO genes polymorphism with T2D was investigated. Methods: Clinical traits in a random sample of 183 Iranian men and wom...
[ 2 ] - بررسی تغییرات الگوی بیان ژن VEGF و القاء آپوپتوز در رده سلولی سرطان پستان MCF-7 تیمار شده با کروسین
Introdution: Targeting vascular endothelial growth factor (VEGF) is considered as a therapeutic goal in solid tumors; especially breast cancer. The use of drugs with natural compounds in the treatment of cancer is increasing because of exerting no adverse effects in normal cells. Crocin, as the main component of saffron, has been proved to have different biological activities on various types o...
[ 3 ] - Silymarin inhibits Toll-like receptor 8 gene expression and apoptosis in Ramos cancer cell line
Objective: Silymarin is a herbal extract containing flavonolignans, and it has inhibitory effects against the growth of different cancer cell lines by inducing apoptosis. Toll-like receptors are suggested as a novel and attractive target to treat cancer. The current study aimed at examining the mechanism of silymarin-induced apoptosis in Ramos cells and investigating its effect...
[ 4 ] - Evaluation of Salivary Interferon-Gamma Level in Patients with Recurrent Aphthous Stomatitis
Introduction: Recurrent aphthous stomatitis (RAS) is defined by recurring ulcers restricted to oral mucosa in the patients with no other signs of systemic disease. The purpose of this study was to evaluate the salivary level of interferon gamma in patients with RAS. Methods: In this case-control study, 30 patients with RAS (in Recurrence and recovery period) in the experimental and 25 healthy ...
[ 5 ] - Assessment the correlation of Morning Nutrition and Demographic Factors with Dental Caries in 9-year-old Students in Zahedan city
Background and Aims: Geographic tongue is a common inflammatory disorder of the tongue whose etiology is unknown. In this study, salivary levels of interferon-gamma were measured in persons with geographic tongue. Materials and Methods: In this case-control study, 30 persons with geographic tongue and 30 healthy individuals who had the conditions to enter the study were evaluated among the pati...