Shabnam Zeighamy Alamdary

[ 1 ] - Effect of morphine on apoptotic factors caspase-3, PARP and Bax/Bcl-2 ratio in nucleus accumbens in conditioned place preference model in rat

Introduction: Nucleus accumbens (NAc) plays a critical role in neuronal reward circuits that are responsible for motivated and goal-directed behaviors. Some data suggest that morphine induces apoptosis in neurons, while other evidences show that morphine could have beneficial effects against neuronal cell death. This study was designed to evaluate the effect of morphine on apoptosis in the N...