Sedigheh khanjani jelodar
[ 1 ] - Effect of Olive Leaf Extract on the Behavioral Signs of Huntington\'s Disease and Antioxidant Enzymatic Activity in the Rat Brain
Introduction: Huntington's disease is a neurodegenerative disorder in which an increase in the global oxidative stress and a decrease in the antioxidant defense system are observed. Olea europaea's main phenolic components include oleuropein, dimethyl oleuropein, ligstroside and phenolic oleosides, which can be more than 140 mg per gram of fresh olives and 60-90 mg per gram of dried olive le...
[ 2 ] - اثر حفاظتی کونژگه دکستران - کورکومین بر اختلال حافظه در مدل حیوانی ایسکمی مغزی فراگیر
زمینه و هدف: سکته ایسکمی علت عمده مرگ‌ومیر در جهان است. در میان اختلالات مشاهده‌‌شده در بازماندگان ایسکمی، اختلال یادگیری شناختی و حافظه به‌صورت قابل‌توجهی وجود دارد. هدف از این مطالعه بررسی اثر حفاظتی کونژگه دکستران - کورکومین بر اختلال حافظه و حجم آسیب مغزی در مدل حیوانی ایسکمی فراگیر مغزی می‌باشد. روش بررسی: در این مطالعه تجربی، 35 سر موش صحرایی در 5 گروه تقسیم‌بندی شدند. گروه‌های پیش‌تیمار ...
[ 3 ] - Antioxidant and Anti-anxiety Effects of Sumac Nano-Phytosome in Rat Model of Alzheimer’s disease: An Experimental Study
Background and Objectives: Alzheimer’s disease (AD) is a neurodegenerative disease accompanied by common emotional symptoms such as anxiety and fear. The aim of this study was investigating the anti-anxiety and antioxidant effects of sumac extract and its nano-phytosome, in streptozotocin (STZ)-induced rat model of Alzheimerchr('39')s disease Materials and Methods: In this experimental study, ...
[ 4 ] - Effect of Sumac Nano-phytosome on Memory and Oxidative Stress in Valproic Acid-induced Rat Model of Autism Spectrum Disorder
Background: Autism Spectrum Disorder (ASD) is an advanced neurological disorder characterized by symptoms such as deficits in social interaction, communication, and cognition. Although sumac fruit contains compounds with antioxidant and anti-inflammatory properties, its effectiveness is limited due to its low bioavailability. Objective: This study aims to investigate the neuroprotective effec...
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