Akbar Vahdati
Department of Biology, Fars Science and Research Branch, Islamic Azad University, Fars, Iran
[ 1 ] - Busulfan induces oxidative stress- and Bcl-2 family gene-related apoptosis in epididymal sperm and testis of adult male mice
Introduction: Busulfan as a chemotherapeutic agent causes testicular germinal epithelium depletion and cytotoxicity in germ cells. The aim of this study was to assess antioxidant status, reactive oxygen species (ROS) generation and apoptosis-related genetic markers of adult male mouse sperm following busulfan treatment. Materials and Methods: Forty adult NMRI mice (30 ± 5 g) were divided...
[ 2 ] - Comparison of the effects of ethinyl estradiol and genistein on serum lipids and lipoproteins of hypercholestrolemic male rats
Introduction: Estrogen is one of the female sex hormones that in addition to its reproductive role, has favorable fects on the metabolism of blood lipids and lipoproteins and by this way decreases the coronary heart disease. n the other hand, phytoestrogens are phytochemical substances that have effects like estrogens. Isoflavones, hich the most important of them is genistein, are the mos...
[ 3 ] - The Regenerative Effect of Bone Marrow-Derived Stem Cells in Spermatogenesis of Infertile Hamster
BACKGROUND Infertility is a serious social problem in advanced nations, with male factor in half of all cases of infertility. This study was conducted to determine the regenerative effect of bone marrow-derived stem cells in spermatogenesis of infertile hamster. METHODS Twelve adult male hamsters were equally divided into azoospermic and control groups. Busulfan was intraperitoneally used fo...
[ 4 ] - اثر محیط کشت حاصل از سلولهای بنیادی مزانشیمیمغز استخوان در درمان ناباروری آزواسپرمیک القاء شده به وسیله بوسولفان در موش بالب– سی
چکیده زمینه و هدف: تجویز داروهای شیمی‌درمانی در بیماران مبتلا به سرطان می‌تواند زمینه‌ساز ناباروری باشد، لذا این مطالعه با هدف بررسی اثر محیط استفاده شده در کشت سلولهای بنیادی مزانشیمیمغز استخوان(سیکریتا) در درمان ناباروری آزواسپرمیک القاء شده به وسیله بوسولفان در موش بالب‌ـ سی انجام گردید. روش بررسی: در این مطالعه تجربی، 18 سر موش سوری از نژاد بالب - سی به صورت تصادفی به سه گروه کنترل، آز...
[ 5 ] - Changes in the Hypothalamic-Pituitary-Gonadal Axis in Adult Male Rats Poisoned with Proteus and Biscaya Insecticides
Background: Insecticides may have negative effects on reproductive organs. Given the interaction between leptin and the hypothalamic-pituitary-gonadal (HPG) axis, we sought to investigate the changes in leptin and the HPG axis in adult male rats poisoned with Proteus and Biscaya insecticides. Methods: Our experimental subjects were 110 adult male Wistar rats (80–90 days of age; average weight=2...
[ 6 ] - Growth Kinetics, Characterization, and Plasticity of Human Menstrual Blood Stem Cells
One of the readily available sources of mesenchymal stem cells (MSCs) is menstrual blood-derived stem cells (Men-SCs), which exhibit characteristics similar to other types of MSCs. This study was performed to determine the growth kinetics, plasticity, and characterization of Men-SCs in women. During spring 2014 in the southern Iranian city of Shiraz, menstrual blood (5 mL) was obtained from 10 ...