Nastaran Eidelkhani
Department of Physiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
[ 1 ] - Doxepin improves stress-impaired long-term potentiation and gene expression of BDNF in the rat hippocampus
Introduction: Stress is associated with neurological and cognitive disorders. It has been suggested that doxepin, in addition to its influence on the content of neurotransmitters, has probable neuroprotective effects as well. Therefore, the aim of this study was to investigate the effects of doxepin on synaptic plasticity and brain-derived neurotrophic factor (BDNF) gene expression in the rat h...
[ 2 ] - Effects of doxepin on spatial memory, TNF-α and Bcl-2 family genes expression in rat hippocampus
Introduction: Although the initial hypothesis for the action of doxepin was based on the inhibition of the reuptake of neurotransmitters, it has been suggested that it may also involve other mechanisms. Therefore, this study aims to investigate the effect of doxepin on spatial memory, tumor necrosis factor alpha (TNF-&alpha) level, expression of pro-apoptotic (Bad and Bax) and anti-apoptotic (B...
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