Sadeghi , Hossein
Department of Medical Genetics, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Medical Cellular & Molecular Research Center, Golestan University of Medical Sciences, Gorgan, Iran
[ 1 ] - Prioritization of rs187728237 and rs80320514 as miRNA-related Variants of Human AEG-1 Gene
ABSTRACT Background and objectives: 3' untranslated region (3'UTR) single nucleotide polymorphisms (SNPs) represent genetic variations that may potentially affect binding of miRNA to coding genes, potentially leading to complex disorders. We aimed to perform in silico analysis of the potential phenotypic effect of 3'UTR S...
[ 2 ] - Impact of Ionizing Radiation on the Expression of CDC25A Phosphatase (in vivo)
Background and Objective: The cell division cycle 25 (CDC25)is a familyof highly conserved dual-specificity phosphatases that activate cyclin-dependent kinase complexes. These complexes are the main cell cycle regulators. Mammalian cells ,exposure to DNA damaging radiations such as ionizing radiation and ultraviolet light, prevent cell cycle progression by activation of checkpoint pathways an...
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