Alireza Mohebbi
[ 1 ] - Low Prevalence of Borna Disease Virus RNA in Patients with Bipolar Major Depression and Schizophrenia in North of Iran
Background and Aims: Borna disease virus (BDV) is well known as a neurotropic virus, however, its role in human neurological diseases such as schizophrenia and bipolar disorder is still unclear. In this study, we aimed to investigate the BDV genome in such patients in Golestan province, North of Iran. Materials and Methods: RNA was extracted from peripheral blood mononuclear cells (PBMCs) from...
[ 2 ] - Identification of Human Cytomegalovirus pUL27 R233 point mutation using PCR-RFLP
Background and Aims: Human Cytomegalovirus (HCMV) is one of the life-threatening agents in immunosuppressed patients and congenitally infected neonates in the world. Mutations in UL27 were suggested to confer low- to high-grade Maribavir (MBV) resistance. As pUL27 R233S variation may involve in either MBV-resistance, we aimed to establish a method for identifying R233 coding sequence mutation...
[ 3 ] - Honey Bee Dry Venom Reduces Hepatitis B Virus Surface Antigen Secretion in PLC/PRF/5 Cell Line
Background and Aims: Currently, many efforts are directed toward functional Hepatitis B virus (HBV) treatment. This is achievable by suppression of HBV surface antigen (HBsAg) secretion. In this regard, use of natural products has been the areas of interest by scientific communities. Materials and Methods: Dried Honey Bee venom was extracted for assessing its anti-HBsAg secretion potential. He...
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