Atiyeh Ale Ahmad
Health Research Institute, Babol University of Medical Sciences, Babol, Iran 2. Student Research Committee, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
[ 1 ] - Taq1 Polymorphism (rs731236) of Vitamin D Receptor Gene in Children with Acute Lymphoblastic Leukemia
Background: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Several studies have shown that ALL occurs as a result of genetic abnormalities. 1, 25-Dihydroxyvitamin D3 as a secosteroid hormone plays an important role in different metabolic pathways. The normal function of vitamin D occurs via binding to a ligand-activated transcription factor i.e. vitamin D receptor (VDR)...
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