Younes Hosseinpour
Pastor Institute of Iran, Tehran, Iran.
[ 1 ] - Interaction of Memantine with Homocysteine on the Apoptosis in the Rat Hippocampus cells
It has been hypothesized that elevated plasma Homocysteine (Hcy) plays a role in the pathogenesis of Alzheimer’s disease (AD) and age-related cognitive decline. The mechanism of Hcy neurotoxicity in the brain is controversial as well Hcy is a ligand of NMDA receptor. Memantine, an uncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors approved for the treatment of moderate to severe ...
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