Caterina Cuppari
Department of Adult and Childhood Human Pathology, Unit of Pediatrics, University Hospital of Messina, Messina, Italy.
[ 1 ] - Neuroinflammation in Autism Spectrum Disorders: the Role of High Mobility Group Box 1 Protein
The pathogenesis of autism spectrum disorder (ASD) likely involves genetic and environmental factors, impacting the complex neurodevelopmental and behavioral abnormalities of the disorder. Scientific researches emerging within the past two decades suggest that immune dysfunction and inflammation have pathogenic influences through different mechanisms, all leading to both a chronic state of low ...
[ 2 ] - Local Allergic Rhinitis in Pediatric Patients: is IgE Dosage in Nasal Lavage Fluid a Usefull Diagnostic Method in Children?
Local Allergic Rhinitis (LAR) is an emerging disease. However, its incidence in the pediatric population has not yet been studied. The gold-standard for the diagnosis is the nasal provocation test that is not everywhere available and difficult to apply in children. The aim of our study is to evaluate the nasal lavage fluid IgE as a biomarker of LAR in children. 54 pediatric patients [IQR 4.0-12...