SM Mirnurollahi
Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
[ 1 ] - Different protein expression systems can influence the direction of the immune responses against HCV core protein in animal model
Introduction: Hepatitis C virus (HCV) infection is a major public health problem which influences about 170 million people worldwide. Different types of vaccines have been designed using HCV structural proteins to control the viral infection. The core nucleocapsid protein is one of the most conserved proteins and a desirable target for HCV vaccines, especially the protein-based vaccines. In cur...
[ 2 ] - Expression and Purification of HCV Core and Core-E1E2 Proteins in Different Bacterial Strains
Background: Hepatitis C virus (HCV) is a main public health problem causing chronic liver infection and subsequently liver cirrhosis and lethal hepatocellular carcinoma (HCC). Vaccination based on HCV capsid proteins has attracted a special interest for prevention of viral infections. The core protein is a basic and evolutionary most conserved protein, which regulates the cellular processes rel...
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