Sadeghi , SA

Department of Research and Development of Hepatitis A vaccine, Pasteur Institute of Iran, Alborz, Iran.

[ 1 ] - Cloning and expression of hepatitis E virus ORF2 as a vaccine candidate

Introduction: Hepatitis E virus (HEV) is a fecal-oral transmitting virus which causes a chronic liver disease. ORF2 is an immunogen capsid protein of HEV that has been proposed to be used for Hepatitis E vaccine design. It is a 660-amino acid protein which includes an immunogenic region (residues 112-607). This protein has been expressed in complete and truncated forms, using different expressi...