Alireza Javadi

Mycobacteriology Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), MasihDaneshvari Hospital, ShahidBeheshti University of Medical Sciences, Tehran, Iran.

[ 1 ] - Evaluation of in-house polymerase chain reaction assay sensitivity, can it be utilized in limited-resources settings?

  Background :Polymerase chain reaction (PCR) assay has widely used for the detection of tuberculosis (TB). This study tried to compare in-house PCR with some well-known commercial PCR kits for detection of TB agent.   Methods : Clinical samples obtained from 620 TB suspected patients were analyzed for the diagnosis of Mycobacterium tuberculosis complex (MTC) by in-house PCR. All samples were o...

[ 2 ] - Comparison of serum PCR assay and histopathology for the diagnosis of invasive aspergillosis and mucormycosis in immunocompromised patients with sinus involvement

Background and Purpose: Invasive fungal infections cause morbidity and mortality in patients with hematologic malignancies and immunosuppression. Although these infections are commonly caused by Candida and Aspergillus species, infections caused by Mucoralean fungi are also on a growing trend. The definitive diagnosis of mucormycosis includes visualization of non-septate hyphae on patholog...