Shima Rokn Sharifi
Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
[ 1 ] - Association of the CTLA-4 1722TC polymorphism and systemic lupus erythematosus: a systematic review and meta analysis
Background :Cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) is an important negative regulator of T-cell responses. The -1722TC polymorphism of the CTLA-4 gene may be associated with systemic lupus erythematosus (SLE) risk, but related results from previous studies have been inconsistent. We carried out a meta-analysis to assess this association more precisely. Methods : A systematic s...
[ 2 ] - Estimating the prevalence and disease characteristics of rheumatoid arthritis in Tehran: A WHO -ILAR COPCORD Study (from Iran COPCORD study, Urban Study stage 1)
Background :To estimate the prevalence and characteristics of Rheumatoid Arthritis (RA) in an urban area of Tehran. Methods : A total of 50 clusters were randomly selected in Tehran and 10291 subjects completed the COPCORD Core Questionnaire during 2004 and 2005. Patients with rheumatic complaints were examined and diagnosed by subspecialty fellows in rheumatology. Laboratory and radiology ...