Saeed Mohammadi
Hematology, Oncology and Stem Cell Transplantation Research Center, Tehran University, Medical Sciences, Tehran, Iran.
[ 1 ] - Microvesicles preparation from mesenchymal stem cells
Background: Extracellular vesicles are particles ranged from 30 nm to 5µm and subcategorized into three groups; exosomes, microvesicles and apoptotic bodies, each of which have different biological impact. Lack of a standard method for the detection and isolation of MVs has led to a challenging issue that is a worth considering. In this study, we isolated MVs from the conditioned medium o...
[ 2 ] - Effect of curcumin and sorafenib on AKT gene expression in KG1 and U937 cell lines
Abstract Background and Objectives Acute myeloid leukemia is a heterozygous hematologic malignancy that is manifested by the accumulation of hematopoietics stem cells in peripheral blood and bone marrow. Anticancer effects and cryotoxic activity of curcumin have been proven frequently in many cancers. Sorafenib is known as an inhibitor of angiogenesis which prevent cells’ survival. In the...
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