Farideh Feizi
Department of Anatomical science, Faculty of Medicine, Babol University of Medical Sciences
[ 1 ] - Time dependent of epigenetic effect of disulfiram on tumor suppressor gene of RASSF1A in Hela cancer cell line
Introduction: Cervical cancer is the third most common tumor among women. Surgery, radiotherapy, and chemotherapy are common treatments, however high stage tumors have frequently poor prognosis. Nowadays, the epigenetic reversion introduced as an efficient strategy of treatment of cervical cancer. In the process, inhibitors of DNA methyltransferase (DNMT) induce re-expression of tumor suppresso...
[ 2 ] - A Study of arbutin protective effect on cyclosporin A-induced oxidative damage
Background: Cyclosporine A (CsA) is a potent immunosuppressant drug with therapeutic and toxic actions. The use of CsA is limited by its toxicity. Several researchers had proposed that oxidative stress could play an important role in CsA-induced toxicity. Arbutin has recently been shown to possess antioxidative and free radical scavenging abilities.The present study was designed to investigate...
[ 3 ] - ارزیابی هیستوپاتولوژیکی عصاره هیدروالکلی‌کبر (Capparis spinosa) برترمیم زخم-دهانی موش سفید زمایشگاهی
سابقه و هدف: عوامل بسیار زیادی در سرعت و چگونگی روند ترمیم زخم موثرند. از اهداف علوم پزشکی، ترمیم زخم در زمان کوتاه با کاهش عوارض جانبی است؛ ازآنجائیکه تاثیر و مکانیسم عملکرد کبر بر ترمیم زخم دهانی شناخته شده نیست لذا در تحقیق حاضر برای اولین بار اثر عصاره هیدروالکلی این گیاه در ترمیم زخم دهانی موش بررسی شده است. مواد و روشها: در این مطالعه تجربی 36 سر موش نر از نژاد ویستار، در محدوده وزنی 200...
[ 4 ] - Myristica fragrans Houtt extract attenuates neuronal loss and glial activation in pentylenetetrazol-induced kindling model
Inflammatory reactions are closely associated with the development and progression of epilepsy. It has been shown that inhibition of pro-inflammatory cytokines, which are released from activated astrocytes and microglia, are considered to be an effective therapeutic approach for the treatment of epileptic disorders. Regarding the anti-inflammatory effects of nutmeg (Myristica fragrans Houtt), t...
[ 5 ] - Myristica fragrans Houtt extract attenuates neuronal loss and glial activation in pentylenetetrazol-induced kindling model
Inflammatory reactions are closely associated with the development and progression of epilepsy. It has been shown that inhibition of pro-inflammatory cytokines, which are released from activated astrocytes and microglia, are considered to be an effective therapeutic approach for the treatment of epileptic disorders. Regarding the anti-inflammatory effects of nutmeg (Myristica fragrans Houtt), t...
[ 6 ] - Effect of Cassia fistula L. aqueous extract in maternal reproductive outcome, some serum indices and fetal anomaly frequency in rat
Background: Cassia fistula was used traditionally as laxative in pregnant women. Nevertheless, its fetal and maternal effects in pregnancy have not been studied yet. Methods: Oral (Lethal Dose, 50%) LD50 was determined in mice. In addition, a control group, pregnant rats in other 5 experimental groups (n=12) received orally C. fistula aqueous extract (500, 1000 and 2000 mg/kg), tween80 (10%) a...
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