Bahareh Sadeghi

Neuroscience Research Center, Baqiyatallah (a.s.) University of Medical Sciences, Tehran, Iran.

[ 1 ] - Effects of Memantine, an NMDA Antagonist, on Metabolic Syndromes in Female NMRI Mice

Introduction: The brain glutamate neurotransmitter system and its NMDA receptors in the nucleus accumbens play an important role in the incidence of the phenomena of sensitivity and addiction. The present study examined the inhibitory effect of glutamate NMDA receptors in the nucleus accumbens in response to chronic stress. Methods: After the unilateral and bilateral cannula placement in the ...

[ 2 ] - Comparison of effect of intraperitoneal vs. intra-accumbal injection of memantine on response to acute stress in female NMRI mice

Introduction: In this study, the effect of memantine administration into the nucleus accumbens on the metabolic changes induced by acute stress in female mice was evaluated. Methods: Intra-accumbens unilateral or bilateral canulation was performed. One week after recovery, a group of animals were given memantine (1, 0.5, and 0.1 μg/mouse) five min before stress induction intra-accumbally, an...