Zahra Ghasemi
Tarbiat Modares University
[ 1 ] - Neuroprotective effect of minocycline on PTZ-induced epileptiform activity and alterations of the shape of action potentials in snail neurons assessed by using intracellular recordings
Introduction: Epilepsy is a neurological disorder that affects 1-2% of the world population and about 30% of patients are resistant to antiepileptic drug therapy. Therefore, new treatment alternatives are needed. In the present study, the possible neuroprotective effect of minocycline against epileptiform activity induced by pentylenetetrazole (PTZ) was assessed. Methods: Conventional intra...
[ 2 ] - Neurostimulation as a Putative Method for Treatment of Drug-Resistant Epilepsy in Patient and Animal Models of Epilepsy
A patient with epilepsy was shown to have neurobiological, psychological, cognitive, and social issues as a result of recurring seizures, which is regarded to be a chronic brain disease.However, despite numerous drug treatments, approximately, 30–40% of all patients are resistant to antiepileptic drugs. Therefore, newer therapeutic modalities are introduced into clinical practice in which invol...
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