Mohsen Mir
Department of Anatomy, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
[ 1 ] - Cisplatin Induce Urinary Space Obstruction and Tubular Necrosis in Rat Kidney
Introduction: Cisplatin is a platinum based antineoplastic drug, which is widely used for treatment of solid tumors. The present investigation was carried out to study the nephrotoxic effects of double dose injection of cisplatin in rats, as an experimental model. Methods: In this experimental study, 45 adult male Sprague Dawley rats with average weight of 200±30 g were randomly divided...
[ 2 ] - Toxic Effects of Cisplatin on Hepatocytes and Liver Enzymes of Rats
Introduction: Cisplatin is an antineoplastic drug, which is widely used for the treatment of solid tumors. However, its clinical usage is limited because of its side effects such as hepatotoxicity. This study aimed to identify toxic effects of cisplatin on hepatocytes of rats. Methods: A total of 45 adult Sprague Dawley rats weighing 200±30 g were randomly divided into ex...
[ 3 ] - Histomorphometric Analysis of Newly-formed Bone Using Octacalcium Phosphate and Bone Matrix Gelatin in Rat Tibial Defects
Background: Repair of bone defects is challenging for reconstructive and orthopedic surgeons. In this study, we aimedto histomorphometrically assess new bone formation in tibial bone defects filled with octacalcium phosphate (OCP),bone matrix gelatin (BMG), and a combination of both.Methods: A total of 96 male Sprague Dawley rats aged 6-8 weeks weighing 120-150 g were randomly allocatedinto thr...