قوطاسلو, عباس
دانشگاه علوم پزشکی ایران، تهران، ایران
[ 1 ] - بررسی ارتباط کم خونی فقرآهن وهیپوتیروئیدی اولیه
Abstract Background: Iron deficiency is the most common nutritional deficiencies in the world. So that 15% of the total world population is involved. The present study examined the association between iron deficiency anemia and primary hypothyroidism and the prevalence of iron deficiency anemia and primary hypothyroidism, respectively, in patients with iron deficiency anemia and primar...
[ 2 ] - Evaluation of PPP2R5C gene expression in Iranian patients with B-Acute lymphoblastic leukemia and its association with clinical and laboratory findings
Introduction: PPP2R5C is one of the regulatory B subunits of protein phosphatase 2A (PP2A), which is a tumor suppressor. PPP2R5C plays a critical role in cell proliferation, differentiation, and transformation. Considering these vital functions, we investigate the gene expression in Iranian patients with B-Acute Lymphoblastic Leukemia (B-ALL) and its association with clinical and laboratory f...
[ 3 ] - Methylation Status of SOX17 and RUNX3 Genes in Acute Leukemia
Background: Several studies have examined the presence of DNA methylation of CpG islands in leukemia. Methylation of SOX17 and RUNX3 genes may play a role in leukemogenesis through silencing tumor suppressor genes. We investigated the methylation status of SOX17 and RUNX3 genes in patients with acute leukemia. Methods: In this case-control study, peripheral blood samples from 100 AML and 10...
[ 4 ] - Analysis of Expression Of SIRT1 Gene In Patients With Chronic Myeloid Leukemia Resistant To Imatinib Mesylate
Background: Chronic myeloid leukemia is a clonal myeloproliferative disease which is characterized by bcr/abl translocation. With the emergence of tyrosine kinase inhibitors such as imatinib mesylate, significant improvement has been made in treatment of this disease. However, drug resistance against this medicine is still an obstacle. SIRT1 is a gene with deacetylase activity which has been de...
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