خوش میرصفا, مجید

دانشگاه علوم پزشکی ایران، تهران، ایران

[ 1 ] - بررسی میزان بیان IL-17 و IL-23R در سلول های تک هسته ای خون محیطی بیماران مبتلا به آرتریت روماتوئید

Background: Rheumatoid arthritis (RA) is an autoimmune disease caused by accumulation of numerous inflammatory cells in the joints and secretion of various cytokines leading to cartilage and bone damage. IL-17 and IL-23 are inflammatory cytokines that their definite role has not been clearly distinguished in RA pathogenesis. Therefore, this study aimed to investigate the expression and associat...

[ 2 ] - میکروRNAهای گردشی، بیومارکرهای ارزشمند در مایعات بیولوژیک بدن

MicroRNAs (miRNAs) are severely protected sequences and single stranded structures approximately 18 to 25 nucleotides in length. The crucial role of miRNAs has been previously proved in the regulation of the gene expression in post transcriptional modification events of messenger RNA. The precise mechanism by which miRNAs modulate translational repression of mRNAs is not fully determined. Howev...